ESKAPE BACTERIA AND ANTIMICROBIAL RESISTANCE

Abstract

Infections caused by multidrug-resistant (MDR) bacteria continue to be a worldwide problem.  Multidrug resistance is growing rapidly among Gram-positive and Gram-negative pathogens that cause infection in the nosocomial environment and the general community.

Several MDR pathogens especially, Klebsiella pneumoniae, Enterococcus faecium,  Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacter spp. and  Acinetobacter baumannii , known as ESKAPE pathogens cause  the main infections within the nosocomial environment. Antibiotics resistance naturally occurs over time but it a slow process. However, the misuse or overuse of antibiotics has accelerated the number of resistant bacteria, which is difficult to eliminate.   Despite, there are still possible treatment options available to eliminate these resistant bacteria in recent days, future attention should focus on avoiding further development of  resistant pathogens. In this review, we will describe the ESKAPE, some of their antibiotics resistant mechanisms and bacterial species belonging to the ESKAPE group