ORGAN-ON-A-CHIP MODELS OF CANCER FOR FUTURE PERSONALIZED MEDICINE- A REVIEW

Abstract

An organ-on-a-chip called or referred to as ‘OOAC’ is a multi 3D microfluidic cell culture chip that stimulates the activities, mechanics, and physiological response of entire organs and organ systems. It can be referred to or even called an artificial organ. In the case of cancer patients, organ-on-a-chip can prove to be of great importance since it can help stimulate the actions of a cancerous cell or even a majorly metastasized cell. Cancer is one of the most dangerous diseases which humans had to battle with since death was one major conclusion when it came to cancer. Cancer is considered to be the topmost concern in the medical field currently. Organ-on-a-chip is one of the recent advances in science and the medical field. It was developed and initiated by famous institutions and universities such as the Wyss Institute and Harvard University. The ‘organ-on-a-chip’ models in cancer would prove to be much more useful and satisfactory than the current in-vitro and in-vivo cancer models which have proven to be incapable in predicting the outcome satisfactorily for various clinical treatments on patients which are hence seen as serious limitations.